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Response to Standard PBC Treatment at 1 Year Linked to Lower Long-Term Risks

MedPage Today ·

Response to Standard PBC Treatment at 1 Year Linked to Lower Long-Term Risks

The Brief

  • A biochemical response to ursodeoxycholic acid (UDCA) at 12 months was associated with lower 5-year risks of hepatic decompensation and mortality in patients with primary biliary cholangitis (PBC).
  • The finding comes from a propensity-matched landmark analysis.

Why it matters

It suggests that response to standard UDCA therapy at one year may help clinicians identify PBC patients with better long-term outcomes.

Who’s affected

  • clinicians treating primary biliary cholangitis
  • patients with primary biliary cholangitis

(MedPage Today) -- A biochemical response to ursodeoxycholic acid (UDCA) at 12 months was associated with lower 5-year risks of hepatic decompensation and mortality in patients with primary biliary cholangitis (PBC), a propensity-matched landmark...

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