Research
Reflux Drugs and Dementia Risk; Epstein-Barr's Link to IBD; Managing Hepatitis Delta
The Brief
- A meta-analysis of nearly two dozen studies found that proton pump inhibitor use in older adults was associated with a modestly increased risk of incident dementia.
- The findings were published in Clinical Pharmacology and Therapeutics and reported by MedPage Today.
Why it matters
The link is modest and observational in nature, so it does not establish that these drugs cause dementia, but it is a relevant signal for clinicians and older patients who take PPIs long term.
Who’s affected
- clinicians prescribing proton pump inhibitors to older adults
- older adults and caregivers who take proton pump inhibitors
- #proton pump inhibitors
- #dementia
- #meta-analysis
- #gastroenterology
- #drug safety
(MedPage Today) -- Use of proton pump inhibitors in older adults was associated with a modestly increased risk of incident dementia, according to a meta-analysis of nearly two dozen studies published in Clinical Pharmacology and Therapeutics....