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Novel GLP-1 Cut Heavy Drinking Days in Alcohol Use Disorder

MedPage Today ·

Novel GLP-1 Cut Heavy Drinking Days in Alcohol Use Disorder

The Brief

  • The investigational glucagon/GLP-1 dual receptor agonist pemvidutide significantly reduced heavy drinking days per week in patients with moderate-to-severe alcohol use disorder.
  • The result comes from the phase II RECLAIM trial, as reported by MedPage Today from AASLD meeting coverage.

Why it matters

Heavy drinking days are a core outcome in alcohol use disorder, so a significant reduction in a phase II trial signals a possible new drug approach for clinicians and researchers, though it is not yet an approved treatment.

Who’s affected

  • clinicians treating alcohol use disorder
  • addiction medicine researchers
  • people following GLP-1 drug development

(MedPage Today) -- The investigational glucagon/GLP-1 dual receptor agonist pemvidutide significantly reduced the number of heavy drinking days (HDDs) per week in patients with moderate-to-severe alcohol use disorder (AUD), the phase II RECLAIM...

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    Novel GLP-1 Cut Heavy Drinking Days in Alcohol Use Disorder – The Morning Science