Clinical research, public health and drug approvals – as research, never as advice.
(MedPage Today) -- Drugmaker Novartis acknowledged Thursday that there have been nine reports of tumors in children treated with its gene therapy onasemnogene abeparvovec (Zolgensma) for spinal muscular atrophy (SMA). Two of the tumor cases were...
(MedPage Today) -- Treatment with both elafibranor (Iqirvo) and seladelpar (Livdelzi) led to alkaline phosphatase (ALP) normalization in the vast majority of patients with primary biliary cholangitis (PBC) who had elevated ALP levels after an incomplete...
(MedPage Today) -- More than 100,000 Hawaii residents who qualify for Medicaid may soon find their doctors prescribing them fresh food as medicine. The script could be for fresh fruit and vegetables, even ahi, beef, chicken, and eggs. The federally...
(MedPage Today) -- More than a third of infants thought to be allergic to peanuts were not actually allergic, an oral food challenge study showed. With the aim of treating peanut allergy among babies who reacted to peanut before 1 year of age...
(MedPage Today) -- Lumateperone (Caplyta) rapidly improved symptoms of acute mania associated with bipolar I disorder, a phase III trial showed. Among 351 patients with or without mixed features, lumateperone demonstrated superiority over placebo...
(MedPage Today) -- Prenatal exposure to both alcohol and tobacco smoke impacted the baby's facial development more than either alone, a longitudinal study from South Africa showed. Three-dimensional facial scans at 1 month and 1 year of age showed...
An AI assistant that conducts telephone consultations with patients is being trialed in the NHS to help clinicians monitor people with long-term illness. In the trial phase, the virtual assistant, called Dora Care, is designed to deliver safe and empathetic phone calls for people…
Using artificial intelligence (AI) to assess heart function from magnetic resonance imaging (MRI) scans more strongly predicts survival than interpretation by clinicians, according to a study published online Nov. 2 in The Lancet Digital Health.
Bariatric surgery is associated with clinically meaningful two-year weight loss after semaglutide or tirzepatide intolerance or inadequate response, according to a study published online Nov. 3 in the Annals of Surgery.
South African researchers are testing "off-the-shelf" immune cells against lymphoma that has returned or resisted treatment, investigating an approach that avoids having to manufacture a separate treatment from each patient's own cells.
Cancer remains among the most deadly diseases worldwide. Globally, more than 300,000 new cases of brain cancer are reported each year, with glioblastoma, an aggressive form of brain cancer, accounting for over 250,000 deaths. The current standard of care involves the use of…
Researchers from the University of California San Diego School of Medicine have found that adding ketamine to a mindfulness-based treatment for opioid use disorder may strengthen people's ability to recognize and respond to signals from their bodies—changes that may help reduce…
In a healthy pregnancy, a finely tuned maternal immune response prevents the mother's body from rejecting the growing fetus. But in some pregnancies, this response goes haywire, leading to a potentially dangerous complication known as chronic placental inflammation. To understand…
Adelaide University researchers have found a DNA "switch" that helps the body stop the growth of the most common form of breast cancer, providing new insights that could help with future treatments. Up to 80% of breast cancer cases are classified as estrogen receptor-positive…