Research
Prevention of Venous Thromboembolism after Total Hip or Knee Replacement
NEJM · By Charles W. Francisthe PEPPER Trial Investigators & the Steering Committee of the PEPPER Trial* ·
The Brief
- A research article titled "Prevention of Venous Thromboembolism after Total Hip or Knee Replacement" was published in the New England Journal of Medicine.
- It appears in Volume 395, Issue 19, on pages 1896-1910, with an issue date of November 12, 2026.
- The source material provided is limited to the title, journal details and link, so study design, sample and results are not reported here.
Why it matters
Venous thromboembolism is a recognised complication after hip and knee replacement, so a high-profile NEJM study on its prevention is relevant to surgeons, hospitals and guideline authors.
Who’s affected
- orthopaedic surgeons and hospital teams
- patients considering or recovering from hip or knee replacement
- #venous thromboembolism
- #hip replacement
- #knee replacement
- #orthopaedics
- #thrombosis prevention
- #clinical medicine
New England Journal of Medicine, Volume 395, Issue 19 , Page 1896-1910, November 12, 2026.