Research
Upfront PCI Still Not Beneficial for Stable CAD as Far Out as 25 Years
The Brief
- Extended follow-up of the COURAGE and ISCHEMIA trials over up to 25 years found no improvement in hard clinical outcomes with upfront PCI versus conservative management in stable coronary artery disease.
- The result was reported from the AHA meeting coverage on MedPage Today dated 2026-11-11.
- The study concerns patients with stable CAD treated with an invasive strategy compared with conservative management.
Why it matters
Long-term evidence that routine upfront PCI does not reduce hard outcomes in stable CAD supports continued use of conservative medical management as a valid first strategy for these patients.
Who’s affected
- cardiologists and physicians treating stable coronary artery disease
- patients with stable coronary artery disease and their clinicians
- COURAGE
- ISCHEMIA
- #cardiology
- #coronary artery disease
- #percutaneous coronary intervention
- #clinical trials
- #long-term outcomes
(MedPage Today) -- A longer horizon did not give patients with stable coronary artery disease (CAD) any improved hard outcomes when getting an invasive strategy over conservative management, according to extended results from the COURAGE and ISCHEMIA...
Timeline
Extended 25-year results of COURAGE and ISCHEMIA trials reported at AHA meeting
MedPageToday.com - medical news for physicians
Upfront PCI Still Not Beneficial for Stable CAD as Far Out as 25 Years