Research
Ibuprofen and Kidney Injury: Study Reveals Who Is Most at Risk
The Brief
- A retrospective active-comparator study found ibuprofen use associated with higher rates of acute kidney injury (AKI) among hospitalized adults.
- The excess AKI risk was concentrated almost entirely in certain patients rather than spread evenly across all users.
- Source coverage is limited to a MedPage Today summary; the identities of the at-risk subgroups are not stated in the provided text.
Why it matters
Clinicians and hospital pharmacists deciding whether to prescribe ibuprofen may need to focus on identifiable higher-risk patients rather than applying a single blanket rule.
Who’s affected
- hospitalised adults taking ibuprofen
- clinicians and hospital pharmacists
- nephrology and medication-safety researchers
- #ibuprofen
- #acute kidney injury
- #nsaids
- #drug safety
- #hospital medicine
(MedPage Today) -- Use of ibuprofen was associated with higher rates of acute kidney injury (AKI) among hospitalized adults, but the excess risk was concentrated almost entirely in certain patients, according to a retrospective active-comparator...