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Research

Greater lean-body-mass decline with tirzepatide than semaglutide in routine care, revealed by body-composition digital phenotyping

Nature ·

The Brief

  • A study reports greater lean-body-mass decline with tirzepatide than with semaglutide in routine care.
  • The comparison was made using body-composition digital phenotyping.
  • The source provided is a nature.com subject feed entry with no summary.

Why it matters

Loss of lean mass during weight-loss treatment is a clinically relevant side effect, so a head-to-head comparison of two widely used drugs in routine care is useful for clinicians and patients.

Who’s affected

  • clinicians prescribing GLP-1 receptor agonists
  • patients using tirzepatide or semaglutide

Timeline

  1. Study published in Medical research (nature.com)

  2. Medical research : nature.com subject feeds

    Greater lean-body-mass decline with tirzepatide than semaglutide in routine care, revealed by body-composition digital phenotyping

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