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Identification of gamma-hydroxybutyrate (GHB)–β-ribose as a promising biomarker enabling prolonged detection of GHB intake

Science · By Kathrine Bohn Faldborg, Jørgen Bo Hasselstrøm, Lambert Kristiansen Sørensen, Camilla Bak Nielsen, Søren Lau Borcher Møller, Thomas B. Poulsen, Mogens Johannsen, Charlotte Uggerhøj Andersen & Kirstine Lykke Nielsen ·

The Brief

  • A study published in Science Advances proposes GHB–β-ribose as a biomarker for GHB intake.
  • The authors describe it as a promising biomarker that could enable prolonged detection of GHB intake.
  • The source material provided contains no further details on methods, sample sizes, or validation.

Why it matters

If validated, a biomarker that remains detectable longer than GHB itself could extend the window in which GHB intake can be confirmed, which matters for toxicology and forensic investigations.

Who’s affected

  • toxicologists and forensic scientists
  • clinicians and investigators who handle suspected GHB exposure

Science Advances, Volume 12, Issue 46 , November 2026.

Timeline

  1. Study published in Science Advances (Volume 12, Issue 46)

  2. science.org

    Identification of gamma-hydroxybutyrate (GHB)–β-ribose as a promising biomarker enabling prolonged detection of GHB intake

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    Identification of gamma-hydroxybutyrate (GHB)–β-ribose as a promising biomarker enabling prolonged detection of GHB intake – The Morning Science