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Common Antibiotic Tied to Pregnancy Loss Risk

MedPage Today ·

Common Antibiotic Tied to Pregnancy Loss Risk

The Brief · written from 3 sources

  • A retrospective, active-comparator cohort study found that doxycycline use for respiratory tract infections or acne during early pregnancy was associated with an increased risk of pregnancy loss.
  • Women exposed to doxycycline in early pregnancy had a higher risk of pregnancy loss than those given other antibiotics.
  • The study was published in Annals of Internal Medicine, and the authors note doxycycline is frequently used by women of childbearing age.

Why it matters

Doxycycline is commonly prescribed to women of childbearing age, so an association with pregnancy loss matters for prescribing decisions and patient counselling. The retrospective observational design shows an association, not proof that the drug causes the loss.

Who’s affected

  • clinicians who prescribe antibiotics to women of childbearing age
  • pregnant women and women planning pregnancy

(MedPage Today) -- Women exposed to doxycycline in early pregnancy had an increased risk of pregnancy loss compared to other antibiotics, a cohort study showed. Doxycycline use for respiratory tract infection was linked with increased pregnancy...

Timeline

  1. Cohort study on doxycycline use in early pregnancy and pregnancy loss published in Annals of Internal Medicine

  2. Medical Xpress - latest medical and health news stories

    Doxycycline use in early pregnancy associated with higher risk of pregnancy loss

  3. Science Media Centre

    expert reaction to study finding use of common antibiotic doxycycline, in early pregnancy is linked to higher risk of pregnancy loss

  4. MedPageToday.com - medical news for physicians

    Common Antibiotic Tied to Pregnancy Loss Risk

Full coverage · 3 sources

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    Common Antibiotic Tied to Pregnancy Loss Risk – The Morning Science