Research2 sources
Doxycycline use in early pregnancy associated with higher risk of pregnancy loss
The Brief · written from 2 sources
- A retrospective active-comparator cohort study found doxycycline use for respiratory tract infections or acne during early pregnancy was associated with an increased risk of pregnancy loss.
- The study was published in Annals of Internal Medicine.
- Doxycycline is a common antibiotic, and the findings concern women of childbearing age who use it frequently.
Why it matters
The study reports an association, not proof of cause, but doxycycline is widely prescribed, so the finding bears on prescribing decisions and the evidence base for drug safety in pregnancy.
Who’s affected
- clinicians and pharmacists prescribing antibiotics to women of childbearing age
- pregnant women and those planning pregnancy
- researchers in pharmacoepidemiology and maternal health
- #doxycycline
- #pregnancy
- #antibiotics
- #pregnancy loss
- #drug safety
A retrospective, active-comparator cohort study found that doxycycline use for respiratory tract infections or acne during early pregnancy was associated with an increased risk for pregnancy loss. Given the frequent use of doxycycline by women of childbearing age, these findings…
Timeline
Study linking early-pregnancy doxycycline use to higher pregnancy loss risk reported in Annals of Internal Medicine
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Doxycycline use in early pregnancy associated with higher risk of pregnancy loss
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expert reaction to study finding use of common antibiotic doxycycline, in early pregnancy is linked to higher risk of pregnancy loss
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Science Media Centre
expert reaction to study finding use of common antibiotic doxycycline, in early pregnancy is linked to higher risk of pregnancy loss - 3h ago ↗
Medical Xpress - latest medical and health news stories
Doxycycline use in early pregnancy associated with higher risk of pregnancy loss