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Virus-like particles enable highly efficient gene editing across porcine and avian in vitro, ex vivo , and in ovo models

PLOS ·

The Brief

  • A study published in PLOS Biology reports gene editing using virus-like particles.
  • The authors report efficient editing in pig (porcine) and bird (avian) models across in vitro, ex vivo and in ovo settings.
  • The provided sources do not include quantitative efficiency figures or other detailed results.

Why it matters

If virus-like particles can deliver gene editing reliably in livestock and avian models, researchers may be able to run such experiments more efficiently, though the available source gives no quantitative detail.

Who’s affected

  • researchers in gene editing and transgenic animal models
  • livestock and poultry biology researchers

by Theresa M. Pauli, Theresa von Heyl, Beate Rieblinger, Sabrina Teresa Schleibinger, Wei Liang, Antonia Schmauser, Mithuoshni Arullmoli, Paul Derrer, Anika Eckstein, Sirradu Jagana, Camila Gatti Corrêa, Krzysztof Flisikowski, Tatiana Flisikowska, Benjamin Schusser Pigs and…

Timeline

  1. Study published in PLOS Biology

  2. PLOS Biology

    Virus-like particles enable highly efficient gene editing across porcine and avian in vitro, ex vivo , and in ovo models

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    Virus-like particles enable highly efficient gene editing across porcine and avian in vitro, ex vivo , and in ovo models – The Morning Science