Research
Toward personalized deep brain stimulation via white matter stimulation and microstructure in depression
Nature · By Ha Neul Song ·
The Brief
- A study of 51 patients receiving deep brain stimulation for treatment-resistant depression was published in Nature Communications.
- The study reports that individual white matter stimulation and white matter integrity jointly influence antidepressant response.
- The findings are presented as a step toward personalised deep brain stimulation via white matter stimulation and microstructure.
Why it matters
It suggests that patient-specific white matter measures could help guide where and how deep brain stimulation is targeted in depression, relevant to neuroscience and psychiatry researchers.
Who’s affected
- neuroscientists and psychiatry researchers
- clinicians working with deep brain stimulation for treatment-resistant depression
- #deep brain stimulation
- #depression
- #white matter
- #neuromodulation
- #personalised medicine
Nature Communications, Published online: 10 November 2026; doi:10.1038/s41467-026-79289-9 A study of 51 patients receiving deep brain stimulation for treatment-resistant depression shows that individual white matter stimulation and integrity jointly influence antidepressant…
Timeline
Study published online in Nature Communications
nature.com
Toward personalized deep brain stimulation via white matter stimulation and microstructure in depression