Research
Topographical mismatch sustains open microchannels in living soft tissue for non-destructive protein biopsy
Nature · By Phuong Thao Le ·
The Brief
- Researchers report a multi-lobed microneedle device that keeps micron-scale conduits open in living soft tissue.
- According to the source, the conduits stay open for seven days.
- The device is described as allowing repeated protein sampling without destructive tissue removal.
Why it matters
Skin-attached devices often become inflamed or collapse, which limits repeated sampling. A device that keeps tissue conduits open could make repeated, non-destructive protein biopsies practical for longitudinal studies.
Who’s affected
- biomedical researchers working on wearable or minimally invasive sampling
- clinical researchers interested in repeated protein monitoring
- #microneedles
- #biopsy
- #wearable sensors
- #soft tissue
- #protein sampling
- #biomedical devices
Nature Communications, Published online: 11 November 2026; doi:10.1038/s41467-026-78755-8 Skin-attached devices can easily inflame or collapse. Here, the authors show a multi-lobed microneedle device that holds micron-scale conduits open for seven days, allowing repeated protein…
Timeline
Published online in Nature Communications
nature.com
Topographical mismatch sustains open microchannels in living soft tissue for non-destructive protein biopsy