Research
The single Cryptosporidium rhoptry sequentially drives invasion and host-parasite interface formation
PLOS ·
The Brief
- Cryptosporidium is a leading cause of diarrheal disease in young children.
- The study examines how a single Cryptosporidium rhoptry drives parasite invasion and the formation of the host-parasite interface in the intestinal epithelium.
- The work was published in PLOS Biology on 2026-11-11.
Why it matters
It clarifies how Cryptosporidium enters and interacts with intestinal cells, a basic mechanism behind a major cause of childhood diarrheal disease.
Who’s affected
- parasitologists and researchers studying apicomplexan parasites
- public health researchers concerned with childhood diarrheal disease
- #cryptosporidium
- #apicomplexa
- #parasitology
- #host-pathogen interaction
- #diarrheal disease
by Allison Cohen, Tim Bergner, Amandine Guérin, Maryse Lebrun, Michael Laue, Christian Klotz, Boris Striepen The apicomplexan parasite Cryptosporidium is a leading cause of diarrheal disease in young children. Within the intestinal epithelium, Cryptosporidium establishes a unique…