Research
The fungal phosphate starvation regulator CtPHO4 couples nutrient adaptation to host colonization through the effector NFC1
Cell Reports · By Jacy Newfeld, Seishiro Aoki, Hiromi Haba, Momoko Takagi, Nozomu Takahashi, Akane Kubota, Motomu Endo & Kei Hiruma ·
The Brief
- Researchers identified a fungal effector, NFC1, that is necessary for root colonization by the conditional plant pathogen C. tofieldiae.
- NFC1 also contributes to perturbing the host's circadian clock.
- NFC1 is tightly suppressed under phosphate deficiency by the fungal transcription factor CtPHO4.
Why it matters
The work links the fungus's nutrient-sensing system to its ability to infect plant roots, which helps explain how nutrient status shapes plant-microbe interactions.
Who’s affected
- researchers studying plant-microbe interactions and fungal pathogens
- #fungal pathogens
- #phosphate starvation
- #plant-microbe interactions
- #circadian clock
- #effectors
Newfeld et al. identified a fungal effector NFC1 that is necessary for root colonization and host circadian clock perturbation by the conditional plant pathogen C. tofieldiae. NFC1 is tightly suppressed under phosphate deficiency by the fungal transcription factor CtPHO4…