Research
The Cdh23tm2a mouse allele causes progressive hearing loss that is not improved by postnatal Cdh23 gene expression
Nature ·
The Brief
- A mouse allele called Cdh23tm2a causes progressive hearing loss.
- Restoring Cdh23 gene expression after birth does not improve this hearing loss.
- The source provides only the headline and feed listing, with no summary, so further details are unknown.
Why it matters
The result suggests that postnatal Cdh23 expression alone may not reverse hearing loss caused by this allele, which matters for researchers using this mouse model or studying gene-based approaches to hearing loss.
Who’s affected
- researchers studying hearing loss and inner-ear genetics
- scientists using Cdh23 mouse models
- Cdh23tm2a
- #hearing loss
- #cdh23
- #mouse model
- #gene expression
- #genetics