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Tau builds up faster in people who develop Alzheimer’s before 65, large PET study finds

PsyPost · By Eric W. Dolan ·

Tau builds up faster in people who develop Alzheimer’s before 65, large PET study finds

The Brief

  • A large PET imaging study reports that people who develop Alzheimer's disease before age 65 tend to show more widespread buildup of toxic tau protein in the brain.
  • The same study reports faster spread of tau in early-onset cases compared with those who develop the condition later in life.
  • The findings were published in Science Translational Medicine, according to PsyPost's coverage.

Why it matters

The results suggest early-onset and late-onset Alzheimer's may differ in how quickly tau pathology spreads, which matters for how researchers interpret disease progression and design studies.

Who’s affected

  • Alzheimer's researchers and neuroimaging scientists
  • clinicians who see patients with early-onset dementia

People who develop Alzheimer’s disease before age 65 tend to have more widespread buildup and faster spread of toxic tau protein in the brain than those who develop the condition later in life, according to a brain-imaging study published in Science Translational Medicine . These…

Timeline

  1. PsyPost reports on the brain-imaging study published in Science Translational Medicine

  2. PsyPost – Psychology News

    Tau builds up faster in people who develop Alzheimer’s before 65, large PET study finds

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    Tau builds up faster in people who develop Alzheimer’s before 65, large PET study finds – The Morning Science