Research
Targeting CD44v3 rescues Entrectinib response in brain metastasis of triple negative breast cancer overexpressing TrkA
Nature ·
The Brief
- The article title reports that targeting CD44v3 rescued entrectinib response in brain metastasis of triple negative breast cancer overexpressing TrkA.
- The source material provides only the headline and feed listing, so the study design and results beyond the title are not available here.
Why it matters
It points to a possible combination strategy, pairing CD44v3 targeting with entrectinib, for brain metastases of triple negative breast cancer that overexpress TrkA.
Who’s affected
- oncology researchers
- clinicians treating triple negative breast cancer with brain metastases
- #breast cancer
- #brain metastasis
- #entrectinib
- #cd44
- #trka