Research
Surface Y RNAs at the gut–immune interface
Nature · By Federica Ungaro ·
The Brief
- The study is published online in Nature Cell Biology on 9 November 2026 (doi 10.1038/s41556-026-02102-8).
- It identifies monocyte surface Y RNAs as amplifiers of histone-driven innate immunity.
- The source describes cell-surface RNAs as an emerging class of active components in immune-cell communication.
Why it matters
It suggests that RNAs on immune-cell surfaces can take part in innate immune signalling, a mechanism that researchers studying gut-immune interactions may need to consider.
Who’s affected
- immunology researchers
- researchers studying RNA biology and gut-immune interactions
- #y rnas
- #innate immunity
- #monocytes
- #histones
- #cell signaling
- #gut immunity
Nature Cell Biology, Published online: 09 November 2026; doi:10.1038/s41556-026-02102-8 Cell-surface RNAs are emerging as active components of immune-cell communication. A study now identifies monocyte surface Y RNAs as amplifiers of histone-driven innate immunity, raising…
Timeline
Study published online in Nature Cell Biology
nature.com
Surface Y RNAs at the gut–immune interface