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Study finds that genetic risk does not explain the maternal effect in type 1 diabetes

Medical Xpress ·

Study finds that genetic risk does not explain the maternal effect in type 1 diabetes

The Brief

  • Children whose mothers have type 1 diabetes develop the disease at about half the rate of children whose fathers have it.
  • Inherited genetic risk alone does not explain this long-observed maternal effect, according to a study led by researchers at the University of Colorado.

Why it matters

The finding shows that inherited genetic risk alone cannot account for the difference between maternal and paternal transmission of type 1 diabetes, so other factors must be considered in research on its causes.

Who’s affected

  • people with type 1 diabetes and their families
  • researchers studying type 1 diabetes genetics and epidemiology

Children whose mothers have type 1 diabetes develop the disease at about half the rate of children whose fathers have it. Inherited genetic risk alone does not explain this long-observed maternal effect, according to a study led by researchers at the University of Colorado…

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    Study finds that genetic risk does not explain the maternal effect in type 1 diabetes – The Morning Science