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Some cancer cells survive chemotherapy by turning into giants

Earth.com · By Luis Arrais ·

Some cancer cells survive chemotherapy by turning into giants

The Brief

  • After a near-lethal chemotherapy dose, some cancer cells stop dividing and swell to many times their normal size.
  • These surviving cells then release chemical signals that a wound uses to recruit the immune system's repair cells.
  • The source is a brief Earth.com summary, and the full study details are not included in it.

Why it matters

Chemotherapy survivors that stop dividing and secrete immune-recruiting signals may help explain how tumors recover after treatment, which could matter for designing follow-up therapies.

Who’s affected

  • oncology researchers
  • cancer biologists
  • clinicians and patients following chemotherapy outcomes

Chemotherapy can kill a cancer cell, but some survivors enter an unusual state. After a near-lethal dose, they stop dividing and swell to many times their normal size. Then they start pumping out the chemical signals a wound uses to call in the immune system’s repair crew. These…

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    Some cancer cells survive chemotherapy by turning into giants – The Morning Science