Research
Scientists wipe out deadly brain tumors in every mouse tested with new cancer therapy
The Brief
- UCSF scientists developed B-SYNC CAR-T cells that stay inactive until they reach the brain, where they switch on.
- In the tested mice, the therapy completely eliminated diffuse midline glioma (DMG) tumors in every mouse.
Why it matters
The results come from mouse studies, so they show promise for brain tumor treatment but do not yet establish a therapy for patients. The approach of a therapy that activates only in the target tissue is a design idea science readers can track in later work.
- #cancer therapy
- #car-t cells
- #glioma
- #brain tumors
- #immunotherapy
Scientists at UC San Francisco have developed a powerful new cancer therapy that remains inactive until it reaches the brain, where it switches on to attack deadly tumors. The engineered immune cells, called B-SYNC CAR-T cells, completely eliminated diffuse midline glioma (DMG)…