Research
Psychedelics show anti-inflammatory effects in sick animals but not healthy ones, meta-analysis finds
PsyPost · By Vladimir Hedrih ·
The Brief
- A systematic review and meta-analysis of laboratory and animal studies found that most report anti-inflammatory effects of psychedelics.
- The effects appear mainly when inflammation is already present, according to the review.
- In mice and rats, psychedelics reduced inflammatory markers in animals with induced inflammation.
Why it matters
The findings suggest that anti-inflammatory effects reported in preclinical psychedelic research may depend on whether inflammation is already present, so results from induced-inflammation models may not apply to healthy subjects.
Who’s affected
- psychopharmacology and immunology researchers
- readers interpreting preclinical psychedelic studies
- #psychedelics
- #inflammation
- #meta-analysis
- #animal-studies
- #pharmacology
A systematic review and meta-analysis found that most laboratory and animal studies report anti-inflammatory effects of psychedelics, but mainly when inflammation is already present. In mice and rats, psychedelics reduced inflammatory markers in animals with induced inflammation…