Research
PANGEA: an integrated cell atlas across diverse biological contexts enables systematic profiling of multicellular responses in human diseases
Nature · By Seongryong Kim ·
The Brief
- PANGEA is described as a single-cell transcriptomic atlas covering 160 human diseases across 48 organs.
- The work was published online in Nature Methods on 12 November 2026 (doi:10.1038/s41592-026-03295-4).
- The atlas is intended to enable systematic profiling of multicellular responses in human diseases.
Why it matters
A single integrated atlas spanning many diseases and organs lets researchers compare cell-level responses across conditions rather than within isolated studies.
Who’s affected
- computational biologists and single-cell researchers
- biomedical researchers studying human disease
- #single-cell
- #transcriptomics
- #cell atlas
- #human disease
- #multicellular responses
Nature Methods, Published online: 12 November 2026; doi:10.1038/s41592-026-03295-4 PANGEA is a comprehensive single-cell transcriptomic atlas of 160 human diseases across 48 organs.
Timeline
PANGEA integrated cell atlas published online in Nature Methods
nature.com
PANGEA: an integrated cell atlas across diverse biological contexts enables systematic profiling of multicellular responses in human diseases