Research
OsCPK17- and OsMPK6-mediated dual phosphorylation of OsPUB12 maintains OsPUB2-regulated OsPUB12 homeostasis and balances rice immunity
Nature · By Guosheng Zhao ·
The Brief
- Study in Nature Communications (published 11 November 2026) reports that OsCPK17 and OsMPK6 phosphorylate OsPUB12 at two sites.
- OsPUB2 degrades OsPUB12 to promote rice immunity, according to the source summary.
- Phosphorylation of OsPUB12 by OsCPK17 and OsMPK6 is reported to fine-tune its stability and the plant's defense response.
Why it matters
The work describes a molecular mechanism that balances stability of an immune regulator in rice, which may inform efforts to understand and engineer crop disease resistance.
Who’s affected
- plant biologists and crop breeders
- researchers studying plant immunity and protein phosphorylation
- #rice
- #plant immunity
- #phosphorylation
- #protein degradation
- #crop disease resistance
Nature Communications, Published online: 11 November 2026; doi:10.1038/s41467-026-79063-x OsPUB2 degrades OsPUB12 to promote rice immunity. Phosphorylation of OsPUB12 by OsCPK17 and OsMPK6 at two sites fine-tunes its stability and the plant’s defense response.
Timeline
Study published online in Nature Communications
nature.com
OsCPK17- and OsMPK6-mediated dual phosphorylation of OsPUB12 maintains OsPUB2-regulated OsPUB12 homeostasis and balances rice immunity