Nuclear TRiC states captured in situ
Molecular Cell · By Huaipeng Xing, Remus R.E. Rosenkranz, Nanako Yokoyama, Agnieszka Obarska-Kosinska, Stefanie Böhm, Dietmar Hammerschmid, Jan Philipp Kreysing, Marina Lusic, Julian D. Langer, Fan Liu & Martin Beck ·
Xing et al. visualize the duty cycle of nuclear TRiC using cryo-electron tomography and identify TRiC interactors in the nucleus. These findings indicate that TRiC may act on misfolded proteins in the nucleus.