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Multifunctional phenyl piperidinyl triazoles targeting cholinesterase: toward next-generation Alzheimer’s therapeutics

Nature ·

The Brief

  • A paper in Scientific Reports describes multifunctional phenyl piperidinyl triazoles designed to target cholinesterase.
  • The compounds are proposed as candidates for next-generation Alzheimer's therapeutics.
  • The source feed provided no summary, so further experimental details are not available from the sources.

Why it matters

It is an early-stage medicinal chemistry study that aims at cholinesterase, a established Alzheimer's drug target, so readers should treat it as preclinical rather than a treatment advance.

Who’s affected

  • researchers in neurodegenerative disease and medicinal chemistry
  • people following Alzheimer's drug development

Timeline

  1. Listed in nature.com subject feed for biological sciences

  2. Biological sciences : nature.com subject feeds

    Multifunctional phenyl piperidinyl triazoles targeting cholinesterase: toward next-generation Alzheimer’s therapeutics

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    Multifunctional phenyl piperidinyl triazoles targeting cholinesterase: toward next-generation Alzheimer’s therapeutics – The Morning Science