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Midbrain somatostatin-expressing cells control pain-suppression during defensive states

eLife · By Coline Riffault ·

The Brief

  • An eLife article reports that midbrain somatostatin-expressing cells control pain suppression during defensive states.
  • The authors note that animals in threatening situations show a range of behavioral and autonomic responses, including inhibition of pain that supports defensive behaviors.
  • The source excerpt does not give the study's methods, sample size, or quantitative results.

Why it matters

The work identifies a specific midbrain cell type involved in suppressing pain during threat responses, which bears on how the brain links pain processing to survival behaviors.

Who’s affected

  • neuroscientists studying pain and defensive behavior

In threatening situations, animals exhibit a broad range of behavioral and autonomic responses. As such, a crucial adaptive response is the inhibition of pain, which facilitates relevant defensive behaviors that promote survival. Whereas the structures and mechanisms involved in…

Timeline

  1. eLife publishes the article on midbrain somatostatin-expressing cells and pain suppression

  2. eLife: latest articles

    Midbrain somatostatin-expressing cells control pain-suppression during defensive states

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    Midbrain somatostatin-expressing cells control pain-suppression during defensive states – The Morning Science