Research
Learning-associated flexibility of cortical taste coding is impaired in Shank3 knockout mice
eLife · By Chi-Hong Wu ·
The Brief
- A study in eLife reports that Shank3 knockout mice show impaired learning-associated flexibility in cortical taste coding.
- The source is a short excerpt; the abstract frames the question of whether sensory processing defects in autism spectrum disorders impair flexible sensory encoding.
Why it matters
Shank3 mutations are a model for autism spectrum disorders, and the study suggests sensory processing deficits in such models may extend to how the brain updates sensory meaning through learning.
Who’s affected
- autism researchers
- neuroscientists studying sensory processing and learning
- #neuroscience
- #autism
- #taste coding
- #shank3
- #sensory processing
The ability to update the valence of sensory perception to influence behavior is crucial for survival. A common phenotype in autism spectrum disorders (ASDs) is defects in sensory processing, but whether these defects impair flexible sensory encoding is largely unexplored. In…
Timeline
eLife published the article Learning-associated flexibility of cortical taste coding is impaired in Shank3 knockout mice
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Learning-associated flexibility of cortical taste coding is impaired in Shank3 knockout mice