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Identification of RNA-binding proteins that regulate circRNAs

Nature ·

The Brief

  • A large-scale screen of RNA-binding proteins was reported in Nature Structural & Molecular Biology.
  • The screen identified factors that can control the production, stability and translation of circular RNAs (circRNAs).
  • The paper is doi:10.1038/s41594-026-01913-5, published online 9 November 2026.

Why it matters

It identifies specific proteins that regulate circRNAs at several steps of their life cycle, which could inform future studies of RNA regulation.

Who’s affected

  • molecular biologists and RNA researchers studying circular RNAs

Nature Structural & Molecular Biology, Published online: 09 November 2026; doi:10.1038/s41594-026-01913-5 A large-scale screen of RNA-binding proteins uncovered factors that can control the production, stability and translation of circular RNAs (circRNAs), revealing both…

Timeline

  1. Paper published online in Nature Structural & Molecular Biology

  2. nature.com

    Identification of RNA-binding proteins that regulate circRNAs

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    Identification of RNA-binding proteins that regulate circRNAs – The Morning Science