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High-fat diet may increase colon cancer risk by changing intestinal stem cells

Medical Xpress ·

High-fat diet may increase colon cancer risk by changing intestinal stem cells

The Brief · written from 2 sources

  • A study in mice published in Stem Cell Reports found that a high-fat diet leaves lasting changes in intestinal stem cells.
  • Researchers at Arizona State University report that these changes could potentially increase the risk of tumor development in the colon.
  • The findings come from mouse research, and an expert from King's College London described it as an interesting mechanistic study.

Why it matters

The study offers a mechanistic link between diet and changes in intestinal stem cells that may relate to colon cancer risk, which can inform future research, though the evidence comes from mice and does not establish the same effect in humans.

Who’s affected

  • colorectal cancer and stem cell researchers
  • anyone interested in how diet may affect colon cancer risk

Researchers at Arizona State University, U.S., have found that a high-fat diet leaves lasting changes in intestinal stem cells, potentially increasing the risk of tumor development.

Timeline

  1. Medical Xpress - latest medical and health news stories

    High-fat diet may increase colon cancer risk by changing intestinal stem cells

  2. Science Media Centre

    expert reaction to study in mice suggesting high-fat diet may increase risk of colon cancer through changes in intestinal stem cells

Full coverage · 2 sources

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