Research
Hidden baseline heterogeneity can mask treatment effects in randomized xenograft studies
Nature ·
The Brief
- A study published in Scientific Reports, hosted on nature.com, reports that hidden baseline heterogeneity can mask treatment effects in randomized xenograft studies.
- The available source is a feed entry with no summary, so methods, sample sizes and results could not be verified.
Why it matters
If baseline differences between animal tumour groups go unnoticed, real treatment effects can be hidden, which affects how researchers interpret xenograft results.
Who’s affected
- Researchers running randomized xenograft studies
- #xenograft
- #preclinical-research
- #randomized-trials
- #baseline-heterogeneity
- #study-design