Research
Found: a protein that drives ageing without unleashing inflammation
Nature ·
The Brief
- In aged mice engineered to lack granzyme K, heart and liver function improved.
- These mice also showed less kidney damage than aged mice with the protein.
- The source describes granzyme K as a protein that drives ageing without unleashing inflammation.
Why it matters
The findings point to granzyme K as a possible target for interventions aimed at age-related organ decline, though the evidence so far comes from mice.
Who’s affected
- ageing and geroscience researchers
- biomedical researchers studying heart, liver and kidney disease
- #ageing
- #granzyme k
- #mice
- #inflammation
- #heart
- #liver
Nature, Published online: 12 November 2026; doi:10.1038/d41586-026-03638-3 Aged mice engineered to lack granzyme K have improved heart and liver function and less kidney damage.
Timeline
Study published online in Nature
nature.com
Found: a protein that drives ageing without unleashing inflammation