Research
First Vesicular Self‐Assembly of Betulinic Acid and Its Applications
ChemistryOpen · By Sukhendu Kar, Soumen Patra, C. V. Yelamaggad & Braja Gopal Bag ·
The Brief
- Betulinic acid, a triterpenoid isolated from Ziziphus jujube, spontaneously formed vesicles in DMSO–water mixtures.
- The vesicles were characterized by AFM, SEM and TEM.
- The vesicles could encapsulate fluorophores and doxorubicin, suggesting potential use in controlled drug delivery.
Why it matters
It reports a new self-assembly behaviour of a natural compound, which may point to a low-cost carrier design for drug delivery, though the work described here is at an early stage.
Who’s affected
- chemists working on self-assembling natural products
- researchers in drug delivery and nanocarrier design
- #betulinic acid
- #vesicles
- #self-assembly
- #drug delivery
- #triterpenoid
Betulinic acid (BA), a triterpenoid isolated from Ziziphus jujube , spontaneously formed vesicles in DMSO–water mixtures. Characterized by AFM, SEM, and TEM, these vesicles could encapsulate fluorophores and doxorubicin, having potential use in controlled drug delivery. Notably…
Timeline
ChemPlusChem table of contents lists the article on the first vesicular self-assembly of betulinic acid
Wiley: ChemPlusChem: Table of Contents
First Vesicular Self‐Assembly of Betulinic Acid and Its Applications