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Finding new life in old chemicals for pharmaceuticals using light-driven chemistry

Phys.org ·

Finding new life in old chemicals for pharmaceuticals using light-driven chemistry

The Brief

  • Drug companies keep large libraries of chemical compounds that are screened for possible pharmaceutical use.
  • Sulfonamides, a class of these compounds, are used in antibiotics and in drugs for type 2 diabetes, hypertension and inflammation.
  • The reported work uses light-driven chemistry to create new compounds from existing chemical libraries.

Why it matters

It suggests a way to reuse existing compound libraries to find new drug candidates, which may speed up pharmaceutical development.

Who’s affected

  • pharmaceutical chemists and drug discovery researchers
  • #photochemistry
  • #drug discovery
  • #sulfonamides
  • #chemical libraries
  • #light-driven chemistry

Drug companies maintain large libraries of chemical compounds that can be screened for potential use in the development of new pharmaceuticals. One class of these compounds, sulfonamides, is used in antibiotics and in drugs to treat type 2 diabetes, hypertension and inflammation…

Timeline

  1. Chemistry News article on light-driven modification of chemical library compounds published

  2. Chemistry News - Biochemistry, Polymers, Materials Science

    Finding new life in old chemicals for pharmaceuticals using light-driven chemistry

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