Research
Few meet major clinical response criteria after treatment escalation for lupus
The Brief
- A study published online Nov. 2 reports that fewer than one-quarter of systemic lupus erythematosus patients meet major clinical response criteria after treatment escalation.
- Black patients were less likely than white patients to meet major clinical response criteria.
Why it matters
Clinicians and researchers evaluating lupus therapies should note that most patients do not reach major clinical response after escalation, and that outcomes differ by race.
Who’s affected
- clinicians treating systemic lupus erythematosus
- lupus researchers and trial designers
- patients with lupus
- #lupus
- #autoimmune disease
- #clinical trials
- #health disparities
- #treatment response
For patients with systemic lupus erythematosus (SLE), fewer than one-quarter meet criteria for major clinical response (MCR) after treatment escalation, with Black patients less likely to meet MCR criteria than white patients, according to a study published online Nov. 2 in The…