Research
Experimental weight-loss drug eases painful knee osteoarthritis in two clinical trials
The Brief
- Two Northwestern University-led Phase III clinical trials tested an experimental weight-loss drug in adults with painful knee osteoarthritis who are overweight or have obesity.
- The trials involved more than 1,000 participants, according to the source.
- The source reports the drug eased pain and improved daily activities such as walking, climbing stairs and standing up from a chair.
Why it matters
Osteoarthritis treatments that address both pain and body weight could change how clinicians manage knee pain in patients with obesity. Science readers should note that the findings come from Phase III trials of an investigational drug, which is not yet approved.
Who’s affected
- Adults with painful knee osteoarthritis who are overweight or have obesity
- #osteoarthritis
- #obesity
- #weight-loss drugs
- #clinical trials
- #knee pain
For people with painful knee osteoarthritis (OA) who are overweight or have obesity, everyday activities such as walking, climbing stairs and standing up from a chair can be difficult. In two Northwestern University–led Phase III clinical trials involving more than 1,000…
Timeline
Medical Xpress reports results of two Phase III trials of experimental weight-loss drug in knee osteoarthritis
Medical Xpress - latest medical and health news stories
Experimental weight-loss drug eases painful knee osteoarthritis in two clinical trials