Research
Experience modifies the synaptome architecture in the developing and adult mouse brain
Nature · By Hanan Woods ·
The Brief
- A Nature Communications paper published 11 November 2026 reports that experience modifies synapse populations across the brain.
- The study covers both the developing and the adult mouse brain.
- Environment and visual input are reported to drive changes in excitatory synapse types and subtypes.
Why it matters
It shows that brain-wide synapse populations shift with experience, which is relevant to researchers studying synaptic plasticity and brain development.
Who’s affected
- neuroscientists studying synaptic plasticity
- developmental neuroscientists
- #synapses
- #neuroscience
- #brain plasticity
- #mouse models
- #brain development
Nature Communications, Published online: 11 November 2026; doi:10.1038/s41467-026-78702-7 The effect of experiences on brain-wide synapse populations is unknown. Here, the authors show that environment and visual input drive changes in excitatory synapse types and subtypes across…
Timeline
Paper published online in Nature Communications
nature.com
Experience modifies the synaptome architecture in the developing and adult mouse brain