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Efficient and accurate mixed model association tool for single-cell eQTL analysis

Nature · By Wei Zhou ·

Nature Genetics, Published online: 06 November 2026; doi:10.1038/s41588-026-02798-2 SAIGE-QTL is a framework for eQTL mapping that directly models single-cell read counts using a Poisson mixed model, achieving improved statistical efficiency and power and enabling rare variant…

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    Efficient and accurate mixed model association tool for single-cell eQTL analysis – The Morning Science