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E2F1 signatures stratify immunotherapy response and reveal YWHAQ vulnerability in esophageal squamous cell carcinoma

Nature ·

The Brief

  • A study reports that E2F1 signatures can stratify immunotherapy response in esophageal squamous cell carcinoma.
  • The study also reports a YWHAQ vulnerability in esophageal squamous cell carcinoma.
  • Only the headline and feed listing were available; the full methods and results were not provided.

Why it matters

If E2F1 signatures reliably separate responders from non-responders to immunotherapy, they could inform patient selection in esophageal squamous cell carcinoma, though the provided sources do not give the supporting data.

Who’s affected

  • cancer researchers
  • oncologists studying immunotherapy biomarkers

Timeline

  1. Listed in nature.com biological sciences subject feed

  2. Biological sciences : nature.com subject feeds

    E2F1 signatures stratify immunotherapy response and reveal YWHAQ vulnerability in esophageal squamous cell carcinoma

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    E2F1 signatures stratify immunotherapy response and reveal YWHAQ vulnerability in esophageal squamous cell carcinoma – The Morning Science