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Common genetic variants matter more in Alzheimer’s than scientists thought

PsyPost · By Eric W. Dolan ·

Common genetic variants matter more in Alzheimer’s than scientists thought

The Brief

  • An international genetic study of more than 2.8 million people identified 127 regions of human DNA associated with Alzheimer's disease.
  • 48 of the 127 regions had not previously been linked to the condition.
  • The research, published in Nature, indicates that common inherited variants contribute more to Alzheimer's risk than previously thought.

Why it matters

The findings expand the known genetic map of Alzheimer's risk, which can guide future research into biological pathways and potential drug targets.

Who’s affected

  • Alzheimer's researchers and geneticists
  • clinicians and people with a family history of dementia

An international genetic study of more than 2.8 million people has identified 127 regions of human DNA associated with Alzheimer’s disease, including 48 regions linked to the condition for the first time. Published in Nature , the research indicates that common inherited variants…

Timeline

  1. PsyPost reports on the Nature-published genetic study of Alzheimer's risk

  2. PsyPost – Psychology News

    Common genetic variants matter more in Alzheimer’s than scientists thought

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    Common genetic variants matter more in Alzheimer’s than scientists thought – The Morning Science