Research
Chip identifies cells by their electrical signature, then separates them with a precisely aimed sound wave
Phys.org ·
The Brief
- A chip identifies cells by their electrical signature rather than by labels.
- After identification, cells are separated using a precisely aimed sound wave.
- The approach aims to avoid the stress and behavior changes caused by extrinsic labeling used in methods like fluorescence-activated cell sorting.
Why it matters
Label-free sorting that avoids stressing cells could make cell-based biomedical assays more reliable and less disruptive to the cells being studied.
Who’s affected
- biomedical researchers working with cell sorting
- laboratory scientists doing cell-based assays
- #cell sorting
- #microfluidics
- #acoustics
- #label-free
- #biotechnology
In biomedicine, sorting cells accurately without damaging them remains a persistent problem. Current methods, like fluorescence-activated cell sorting, rely on labeling the cells extrinsically, which can stress the cells, alter their behavior and even interfere with the assay. A…