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Chip identifies cells by their electrical signature, then separates them with a precisely aimed sound wave

Phys.org ·

Chip identifies cells by their electrical signature, then separates them with a precisely aimed sound wave

The Brief

  • A chip identifies cells by their electrical signature rather than by labels.
  • After identification, cells are separated using a precisely aimed sound wave.
  • The approach aims to avoid the stress and behavior changes caused by extrinsic labeling used in methods like fluorescence-activated cell sorting.

Why it matters

Label-free sorting that avoids stressing cells could make cell-based biomedical assays more reliable and less disruptive to the cells being studied.

Who’s affected

  • biomedical researchers working with cell sorting
  • laboratory scientists doing cell-based assays

In biomedicine, sorting cells accurately without damaging them remains a persistent problem. Current methods, like fluorescence-activated cell sorting, rely on labeling the cells extrinsically, which can stress the cells, alter their behavior and even interfere with the assay. A…

Timeline

  1. Chip cell-sorting study reported in Biology News

  2. Biology News - Evolution, Cell theory, Gene theory, Microbiology, Biotechnology

    Chip identifies cells by their electrical signature, then separates them with a precisely aimed sound wave

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    Chip identifies cells by their electrical signature, then separates them with a precisely aimed sound wave – The Morning Science