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CAR-T Therapy: Mixed Results in Rheumatoid Arthritis Trial

MedPage Today ·

CAR-T Therapy: Mixed Results in Rheumatoid Arthritis Trial

The Brief

  • A trial of CAR T-cell therapy in rheumatoid arthritis showed mixed results, according to research presented in Orlando.
  • The research suggested that rheumatoid arthritis may not respond to CAR T-cell therapy as well as lupus and certain other autoimmune conditions have.
  • The source is a meeting report from MedPage Today, published 2026-11-10.

Why it matters

CAR T-cell therapy has drawn interest as a treatment for autoimmune diseases, so results suggesting weaker effects in rheumatoid arthritis matter for how researchers prioritise and interpret trials in that field.

Who’s affected

  • rheumatologists
  • researchers developing CAR T-cell therapies for autoimmune disease

(MedPage Today) -- ORLANDO -- Rheumatoid arthritis (RA) may not be as amenable to chimeric antigen receptor (CAR) T-cell therapy as has been the case in lupus and certain other autoimmune conditions, research presented here suggested. Among...

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    CAR-T Therapy: Mixed Results in Rheumatoid Arthritis Trial – The Morning Science