Research
Blocking excess scarring helps prevent heart failure development
The Brief
- Researchers prevented severe heart failure in a mouse model of heart attack by blocking a protein linked to excess scar tissue.
- Excess scar tissue in the heart contributes largely to most heart failure cases, and currently has no treatments.
- The findings come from a mouse model; the source reports no human trial results.
Why it matters
It points to a possible new therapeutic target for heart failure, a condition that currently lacks treatments aimed at excess cardiac scarring, though the evidence so far is from mice.
Who’s affected
- cardiologists and heart failure researchers
- patients at risk of heart failure after heart attack
- #heart failure
- #cardiac fibrosis
- #heart attack
- #scar tissue
- #mouse model
Most heart failure cases are caused to a large degree by a buildup of excess scar tissue in the heart, which currently has no treatments. Now, researchers have successfully prevented the development of severe heart failure in a mouse model of heart attack by blocking a protein…