Research
Bioengineered Liver System Passes Safety Test in Phase I Trial
The Brief
- A single-use bioengineered liver paired with an extracorporeal blood circuit was tested in a small phase I trial.
- The system replicates key functions of a human liver.
- It was shown to be safe among patients with syndromes of liver failure.
Why it matters
It is an early safety result for an extracorporeal bioengineered liver support approach in patients with liver failure, a step toward clinical use, though a small phase I trial cannot establish efficacy.
Who’s affected
- patients with liver failure
- hepatologists and liver transplant clinicians
- researchers in bioengineering and regenerative medicine
- #liver failure
- #bioengineering
- #clinical trial
- #extracorporeal therapy
- #hepatology
(MedPage Today) -- A single-use bioengineered liver paired with an extracorporeal blood circuit that replicates key functions of a human liver was shown to be safe among patients with syndromes of liver failure in a small phase I trial. There...