Research
Antagonistic second-messenger signalling coordinates Pseudomonas aeruginosa surface colonization and virulence
Nature · By Maya Bruderer ·
The Brief
- Study published in Nature Communications on 7 November 2026 examines Pseudomonas aeruginosa surface colonization and virulence.
- The second messengers cAMP and c-di-GMP regulate surface behaviours and virulence in this bacterium.
- The authors report how the bacteria switch between attachment and surface-associated states, with the two signalling systems acting antagonistically.
Why it matters
Pseudomonas aeruginosa is a significant opportunistic pathogen, so clarifying how its signalling controls surface attachment and virulence may inform future research into bacterial infection.
- #pseudomonas aeruginosa
- #second messengers
- #c-di-gmp
- #camp
- #virulence
- #bacterial signalling
Nature Communications, Published online: 07 November 2026; doi:10.1038/s41467-026-79432-6 Second messengers cAMP and c-di-GMP regulate surface behaviours and virulence in Pseudomonas aeruginosa. Here, the authors show how the bacteria switch between attachment and surface…
Timeline
Published online in Nature Communications
nature.com
Antagonistic second-messenger signalling coordinates Pseudomonas aeruginosa surface colonization and virulence