Research
A single CRISPR infusion lowers blood fats in monkeys for three years
The Brief
- A single CRISPR infusion lowered blood fats (LDL cholesterol and triglycerides) in monkeys for three years, according to Medical Xpress.
- LDL cholesterol and triglycerides are major contributors to atherosclerotic cardiovascular disease.
- The source describes gene editing as a potential alternative to lipid-lowering medications; the study is a preliminary animal experiment.
Why it matters
Gene editing that durably lowers blood fats in primates could, if it translates to humans, offer an alternative to daily lipid-lowering drugs for cardiovascular risk.
Who’s affected
- cardiologists and lipidologists
- researchers in gene editing and cardiovascular medicine
- #crispr
- #gene editing
- #cholesterol
- #cardiovascular disease
- #primate research
High levels of LDL cholesterol and triglycerides, which are types of blood fats, are major contributors to atherosclerotic cardiovascular disease. Gene-editing technologies offer a potential alternative to lipid-lowering medications. In a new CRISPR experiment, a single infusion…