# Toward personalized deep brain stimulation via white matter stimulation and microstructure in depression

Source: [nature.com](https://www.nature.com/articles/s41467-026-79289-9) · 2026-11-10 · Life
Page: https://themorning.science/story/toward-personalized-deep-brain-stimulation-via-white-matter-stimulation-and-micr-b5f0181b85879a87
Kind: research · Impact: low

## In brief

- A study of 51 patients receiving deep brain stimulation for treatment-resistant depression was published in Nature Communications.
- The study reports that individual white matter stimulation and white matter integrity jointly influence antidepressant response.
- The findings are presented as a step toward personalised deep brain stimulation via white matter stimulation and microstructure.

## Why it matters

It suggests that patient-specific white matter measures could help guide where and how deep brain stimulation is targeted in depression, relevant to neuroscience and psychiatry researchers.

## Timeline

- 2026-11-10: Study published online in Nature Communications

## Coverage

- [Toward personalized deep brain stimulation via white matter stimulation and microstructure in depression](https://www.nature.com/articles/s41467-026-79289-9) — nature.com, 2026-11-10

Tags: deep brain stimulation, depression, white matter, neuromodulation, personalised medicine

---

Brief generated by AI (claude-haiku-5-5) from the reporting listed under Coverage. Headlines belong to their publishers. The Morning Science – https://themorning.science