# Targeting CD44v3 rescues Entrectinib response in brain metastasis of triple negative breast cancer overexpressing TrkA

Source: [Biological sciences : nature.com subject feeds](https://www.nature.com/articles/s41392-026-03049-w) · 2026-11-10 · Life
Page: https://themorning.science/story/targeting-cd44v3-rescues-entrectinib-response-in-brain-metastasis-of-triple-nega-e00ee41414d23d51
Kind: research · Impact: low

## In brief

- The article title reports that targeting CD44v3 rescued entrectinib response in brain metastasis of triple negative breast cancer overexpressing TrkA.
- The source material provides only the headline and feed listing, so the study design and results beyond the title are not available here.

## Why it matters

It points to a possible combination strategy, pairing CD44v3 targeting with entrectinib, for brain metastases of triple negative breast cancer that overexpress TrkA.

## Coverage

- [Targeting CD44v3 rescues Entrectinib response in brain metastasis of triple negative breast cancer overexpressing TrkA](https://www.nature.com/articles/s41392-026-03049-w) — Biological sciences : nature.com subject feeds, 2026-11-10

Tags: breast cancer, brain metastasis, entrectinib, cd44, trka

---

Brief generated by AI (claude-haiku-5-5) from the reporting listed under Coverage. Headlines belong to their publishers. The Morning Science – https://themorning.science